Category: News & Events

Angiography-Based Computational Modeling for In Vivo Assessment of Endothelial Dynamic Strain in Coronary Arteries with De Novo Lesions: Comparison of Treatment Effects of Drug-Coated Balloons Between Small and Large Arteries

Angiography-Based Computational ModelingAnnouncing a new article publication for Cardiovascular Innovations and Applications journal. Acute morphological changes in de novo coronary lesions after drug-coated balloon (DCB) angioplasty can affect endothelial mechanics and consequently clinical outcomes.

Angiography-based computational modeling has been validated to assess endothelial dynamic strain (EDS) in coronary arteries in vivo. The EDS was calculated on the basis of pre- and post-DCB angiography. Parameters of quantitative coronary angiography and EDS were quantified at cross-sections in the treated segments. A total of 336 and 348 lesion cross-sections were included in the small/large vessel groups, respectively. (more…)

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Atrial Fibrillation and Adipokines: A Pathophysiological Perspective

Announcing a new article publication for Cardiovascular Innovations and Applications journal.  Atrial fibrillation (AF) is a prevalent cardiac arrhythmia characterized by irregular and frequently rapid electrical activity in the atria. Adipokines are bioactive molecules that are secreted by adipose tissue, and exert diverse effects on health and disease.

Obesity is a complex condition influenced by multiple interconnected factors, and the specific mechanisms linking obesity to AF may vary among individuals. Obesity contributes to the development of atrial arrhythmia. Moreover, obesity plays major roles in the pathophysiology of AF and its associated complications by inducing systemic changes, including altered hemodynamics, heightened sympathetic tone, and a persistent low-grade inflammatory state.

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Identifying Risk Factors for Native Coronary Atherosclerosis Progression After Percutaneous Coronary Intervention

Identifying Risk Factors for Native Coronary Atherosclerosis ProgressionAnnouncing a new article publication for Cardiovascular Innovations and Applications journal. This study was aimed at investigating factors influencing the progression of native coronary atherosclerosis after percutaneous coronary intervention (PCI).

A cohort of 462 patients was classified into progressive (n = 73) or non-progressive (n = 389) groups according to the presence of native coronary atherosclerosis progression on coronary angiography. Clinical data and angiography results were compared during follow-up, and the time to progression of native coronary atherosclerosis was recorded. Subsequently, multivariate Cox regression analysis was conducted.

In comparison to the non-progressive group, the progressive group had higher levels of glycosylated hemoglobin (HbA1c) and triglycerides (TG), and higher scores on the Synergy Between PCI with Taxus and Cardiac Surgery (SYNTAX) scale, but lower levels of high-density (more…)

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Immediate Interventional Management of Aortocoronary Dissection During PCI

Immediate Interventional Management of Aortocoronary Dissection During PCIAnnouncing a new article publication for Cardiovascular Innovations and Applications journal.   Aortocoronary dissection is a rare and potentially fatal complication of percutaneous coronary intervention. It is more common when performing interventions of the right coronary artery or during revascularization of chronic total occlusions. Here, it is aimed to provide more data regarding a less common form of this complication. The case of an 81-year old woman admitted with an acute infero-lateral myocardial infarction, who was indicated for emergency primary coronary intervention is presented. After revascularization of the left circumflex artery, the left main coronary artery exhibited retrograde dissection into the ascending aorta. (more…)

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High-Risk Percutaneous Coronary Intervention: Challenges and Considerations

Announcing a new article publication for Cardiovascular Innovations and Applications journal.

As global life expectancy increases, cardiologists increasingly face challenges of caring for an older population requiring complex coronary revascularization. A substantial portion of these patients are deemed unsuitable for surgery because of their comorbidities, coronary lesion characteristics, and hemodynamic status. In response to the therapeutic needs of this patient cohort, innovative devices and techniques have been developed to provide viable options for treatment. In assessing these patients, the heart team approach is critical, to identify anatomic, hemodynamic, and procedural characteristics that favor adjunctive MCS support. The available data support using adjunct MCS devices in patients with severely reduced LV function (EF < 35%) or in acute decompensated heart failure in the presence of complex coronary artery disease. (more…)

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Delirium in the Cardiac Patient

Announcing a new article publication for Cardiovascular Innovations and Applications journal.  The Diagnostic and Statistical Manual of Mental Disorders, 5th Edition (DSM-5) defines delirium as a disturbance in attention and awareness that develops over a short period and involves fluctuation in severity. This profile is also accompanied by an additional disturbance in cognition (e.g., memory), which are not explained by a preexisting neurocognitive disorder. Arousal levels, such as those in patients in a coma, must also not be severely reduced. Finally, to make the diagnosis of delirium, there must be evidence that the disturbance is a direct physiological consequence of another medical condition, substance intoxication or withdrawal, exposure to a toxin, or due to multiple etiologies.

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Current Outcomes after Revascularization for Coronary Very Late Stent Thrombosis

Announcing a new article publication for Cardiovascular Innovations and Applications journal.  Limited data are available regarding current outcomes after revascularization for angiographically confirmed very late stent thrombosis (VLST). Therefore, this study investigated the current outcomes of patients with VLST and the risk factors for major adverse cardiovascular events (MACE).

Consecutive patients who underwent revascularization for angiographically confirmed VLST between January 2014 and January 2016 were enrolled in this study. The patients were divided into two groups according to the occurrence of MACE during follow-up. The clinical and interventional parameters between groups were compared.

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Case Report: Optical Pumped Magnetometer Magnetocardiography as a Potential Method of Therapy Monitoring in Fulminant Myocarditis

Announcing a new article publication for Cardiovascular Innovations and Applications journal. Fulminant myocarditis (FM) is associated with high mortality and an unfavorable long-term prognosis. However, noninvasive, rapid diagnostic and monitoring methods for FM are lacking.

This article details the case of a patient diagnosed with FM through a comprehensive assessment involving typical clinical symptoms, laboratory analyses, echocardiographic evidence, and cardiac magnetic resonance (CMR) findings.

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Heart Failure Registries in Asia – What Have We Learned?

Announcing a new article publication for Cardiovascular Innovations and Applications journal. Heart Failure (HF) is one of the leading problems in cardiology practice today. Acute decompensated heart failure (ADHF) is a significant cause of mortality and morbidity worldwide, and this is more relevant in the Asian subcontinent with a high population burden.

Various regional registries in Asia have given us valuable insight into the aetiology and outcomes in this context. Though there are regional differences, it is clear from the review carried out in this paper that HF affects a much younger population.

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Comparison of the “Late Catch-Up” Phenomenon Between BuMA Supreme and XIENCE Stents Through Serial Optical Coherence Tomography at 1–2 Month and 2 Year Follow-Ups: A Multicenter Study

Comparison of the “Late Catch-Up” Phenomenon Between BuMA Supreme and XIENCE StentsAnnouncing a new article publication for Cardiovascular Innovations and Applications journal. This study was aimed at comparing the “late catch-up” phenomenon between the BuMA Supreme bioresorbable polymer sirolimus-eluting stent and the XIENCE stent through serial optical coherence tomography (OCT) at within 2 months and 2 year follow-ups.

A total of 49 of 75 patients from the PIONEER-II study were enrolled in a 2 year OCT follow-up study; 44 patients with 50 lesions were included in the statistical analysis. The primary endpoints were neointimal thickness and late luminal loss (LLL) after stent implantation. (more…)

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