Effects of Pharmacological and Surgical Treatments on Mitral Regurgitation Regression and Left Heart Structures: A Meta-Analysis

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Announcing a new article publication for Cardiovascular Innovations and Applications journal providing fresh evidence on the effectiveness of medical and surgical treatments for mitral regurgitation (MR).

Drawing on 24 randomized controlled trials involving 3,711 patients, researchers found that medical therapy was associated with reductions in MR severity, while transcatheter mitral valve repair (TMVr) and mitral valve surgery (MVS) showed comparable benefits in reducing recurrent MR. The findings also highlight the potential value of combining appropriate surgical intervention with sustained optimal medical therapy to improve left heart structure and function, offering important insights for the clinical management of patients with MR.

Read more: https://www.scienceopen.com/hosted-document?doi=10.15212/CVIA.2026.0024

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Hongwei Li, Shaohua Wang and Qian Chen et al. Effects of Pharmacological and Surgical Treatments on Mitral Regurgitation Regression and Left Heart Structures: A Meta-Analysis. CVIA. 2026. Vol. 11(1). DOI: 10.15212/CVIA.2026.0024

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