Myocardial Infarction Archives

Tag: Myocardial Infarction

The Plausible Role of Vascular Adhesion Molecules in Cardiovascular Diseases

Announcing a new article publication for Cardiovascular Innovations and Applications journal. Vascular Adhesion Molecules (VAMs) appear to play important roles in the development of Cardiovascular Diseases (CVD). The roles of these molecules in mediating inflammation, endothelial dysfunction, and plaque formation suggest that they may be important as both biomarkers and therapeutic targets.

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Causal Relationship between PECAM-1 Level and Cardiovascular Diseases: A Mendelian Randomization Study

Announcing a new article publication for Cardiovascular Innovations and Applications journal. Platelet endothelial cell adhesion molecule (PECAM-1) is present in the vascular endothelium and plays important roles in various biological processes. Several recent studies have reported associations between PECAM-1 and cardiovascular diseases (CVDs). However, further research is necessary to clarify the causal effects of PECAM-1 on CVDs.

To determine whether PECAM-1 and CVDs are causally associated, the authors of this article conducted a two-sample Mendelian randomization (TSMR) study.

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Adverse Outcomes in Non-ST-Elevation Acute Coronary Syndrome: A Cluster Analysis Study

Announcing a new article publication for Cardiovascular Innovations and Applications journal. Patients with non-ST-elevation acute coronary syndrome (NSTE-ACS) have diverse clinical trajectories and form a heterogeneous group. They exhibit differences in clinical and angiographic findings, laboratory parameters including platelet function, and the severity of concomitant pathology. These variations affect their clinical courses and prognosis. (more…)

Immediate Interventional Management of Aortocoronary Dissection During PCI

Announcing a new article publication for Cardiovascular Innovations and Applications journal. Aortocoronary dissection is a rare and potentially fatal complication of percutaneous coronary intervention. It is more common when performing interventions of the right coronary artery or during revascularization of chronic total occlusions. Here, it is aimed to provide more data regarding a less common form of this complication. The case of an 81-year old woman admitted with an acute infero-lateral myocardial infarction, who was indicated for emergency primary coronary intervention is presented. After revascularization of the left circumflex artery, the left main coronary artery exhibited retrograde dissection into the ascending aorta. (more…)

Overview of Injectable Hydrogels for the Treatment of Myocardial Infarction

Announcing a new article publication for Cardiovascular Innovations and Applications journal. Myocardial infarction (MI) triggers adverse remodeling mechanisms, thus leading to heart failure. Since the application of biomaterial-based scaffolds emerged as a viable approach for providing mechanical support and promoting cell growth, (more…)

Prognostic Value of Neutrophil-to-lymphocyte Ratio for Patients with Acute Coronary Syndrome and Obstructive Sleep Apnea

Announcing a new article publication for Cardiovascular Innovations and Applications journal. This study was aimed at investigating the effects of the neutrophil-to-lymphocyte ratio (NLR) on the long-term prognosis of patients with acute coronary syndrome (ACS) and obstructive sleep apnea (OSA).

This prospective study enrolled patients (more…)

Exosomal circRNA-0008302 from Adipose-derived Stem Cells Protects Against Myocardial Injury

Announcing a new article publication for Cardiovascular Innovations and Applications journal. This study was aimed at investigating the expression and therapeutic potential of circRNAs from adipose-derived stem cell (ADSC) exosomes (ADSC-Exos) for cardiomyocyte injury.

Differentially expressed circRNAs were screened between ADSCs (more…)

Angiotensin-converting Enzyme Inhibitors Decrease the Risk of Cardiac Rupture after Acute Myocardial Infarction: A Meta-analysis of Randomized Controlled Trials

Announcing a new article publication for Cardiovascular Innovations and Applications journal. ACEI therapy decreases mortality in patients with acute MI. However, the effects of ACEIs on CR are unclear.

A comprehensive search of PUBMED, EMBASE, ISI Web of Science, MEDLINE and the Cochrane Register of Controlled Trials before July 2022 was conducted to identify all RCTs on ACEIs that recorded CR as an outcome. Review Manager 5.3 was used to analyze the data.

Five RCTs including 26,383 patients with MI were identified; 71 of the 13,159 patients receiving ACEIs and 107 of the 13,224 control patients were verified to have CR. ACEI therapy started within 24 hours after the onset of acute MI significantly decreased the risk of CR, by 33% (RR: 0.67, 95% CI: 0.50–0.90, P=0.008).

Early administration of ACEIs (within 24 hours after the onset of acute MI) decrease the incidence of CR in patients with acute MI.

https://www.scienceopen.com/hosted-document?doi=10.15212/CVIA.2023.0040

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Siyi Li, Jinan Wang and Yan Yan et al. Angiotensin-converting Enzyme Inhibitors Decrease the Risk of Cardiac Rupture after Acute Myocardial Infarction: A Meta-analysis of Randomized Controlled Trials. CVIA. 2023. Vol. 8(1). DOI: 10.15212/CVIA.2023.0040