Tag: Myocardial Infarction

Circulating TGM2 Levels as a Prognostic Biomarker for Coronary Artery Disease Severity and Major Adverse Cardiac Events in Acute Coronary Syndrome

Announcing a new article publication for Cardiovascular Innovations and Applications journal. Transglutaminase 2 (TGM2) has been implicated in various health conditions, yet its role in acute coronary syndrome (ACS) remains poorly characterized in clinical settings. This study investigated the association between circulating TGM2 levels and the severity of coronary stenosis in ACS.

A total of 242 individuals with ACS were included in this study. Clinical data were collected, and the severity of coronary stenosis was evaluated with the Gensini and Syntax scoring systems. Kaplan-Meier analysis, logistic regression, and receiver operating characteristic (ROC) curve analysis were performed.

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Comprehensive Bioinformatics Method to Explore Immune-Related Genes in the Pathogenesis of Myocardial Infarction

Announcing a new article publication for Cardiovascular Innovations and Applications journal.   This study was aimed at exploring immune-related genes and their expression changes in myocardial infarction (MI) through comprehensive bioinformatics methods and validating these genes as potential diagnostic and therapeutic targets.

Gene expression data were analyzed from three datasets: GSE29111 and GSE66360, which were combined as a training set, and GSE48060, which served as the validation set.

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A Large-Diameter Thrombus Retrieving Device for Intermediate-Risk Acute Pulmonary Embolism Treatment: A Single-Arm Prospective Clinical Trial

Device for Intermediate-Risk Acute Pulmonary Embolism TreatmentAnnouncing a new article publication for Cardiovascular Innovations and Applications journal.  Globally, acute pulmonary embolism (PE) is the third leading cause of cardiovascular-related deaths after myocardial infarction and stroke. Several studies have reported increased annual incidence of PE and consequently social medical burden. Determining how to treat acute PE more safely and effectively, while decreasing long-term complications, remains an important issue in medicine.

The aim of this study was to report the results of a single-arm clinical trial in (more…)

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Causal Relationship between PECAM-1 Level and Cardiovascular Diseases: A Mendelian Randomization Study

Announcing a new article publication for Cardiovascular Innovations and Applications journal. Platelet endothelial cell adhesion molecule (PECAM-1) is present in the vascular endothelium and plays important roles in various biological processes. Several recent studies have reported associations between PECAM-1 and cardiovascular diseases (CVDs). However, further research is necessary to clarify the causal effects of PECAM-1 on CVDs.

To determine whether PECAM-1 and CVDs are causally associated, the authors of this article conducted a two-sample Mendelian randomization (TSMR) study.

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Adverse Outcomes in Non-ST-Elevation Acute Coronary Syndrome: A Cluster Analysis Study

Non-ST-Elevation Acute Coronary SyndromeAnnouncing a new article publication for Cardiovascular Innovations and Applications journal. Patients with non-ST-elevation acute coronary syndrome (NSTE-ACS) have diverse clinical trajectories and form a heterogeneous group. They exhibit differences in clinical and angiographic findings, laboratory parameters including platelet function, and the severity of concomitant pathology. These variations affect their clinical courses and prognosis. (more…)

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Immediate Interventional Management of Aortocoronary Dissection During PCI

Immediate Interventional Management of Aortocoronary Dissection During PCIAnnouncing a new article publication for Cardiovascular Innovations and Applications journal.   Aortocoronary dissection is a rare and potentially fatal complication of percutaneous coronary intervention. It is more common when performing interventions of the right coronary artery or during revascularization of chronic total occlusions. Here, it is aimed to provide more data regarding a less common form of this complication. The case of an 81-year old woman admitted with an acute infero-lateral myocardial infarction, who was indicated for emergency primary coronary intervention is presented. After revascularization of the left circumflex artery, the left main coronary artery exhibited retrograde dissection into the ascending aorta. (more…)

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