distal transradial access Archives

Announcing a new article publication for Cardiovascular Innovations and Applications journal. With distal transradial access (dTRA), the postoperative compression time remains significantly longer than the recommended range via in practice. This study investigates whether intravenous protamine sulfate might shorten the postoperative compression time and increase safety after coronary angiography via dTRA.

In this retrospective study, patients who underwent coronary angiography were enrolled and divided into two groups. The study group received a slow intravenous injection of 15–20 mg protamine sulfate before sheath retraction. The primary endpoint was the puncture compression time after coronary angiography.

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Announcing a new article publication for Cardiovascular Innovations and Applications journal. Although transradial access (TRA) has become the main vascular access for coronary intervention, its high radial artery occlusion rate limits its application in some patients. Studies have shown that compared with TRA, distal transradial access (dTRA) with the snuffbox area or the Hegu acupoint area as the puncture point significantly decreases the incidence of radial artery occlusion. However, no randomized controlled study has confirmed the safety and efficacy of coronary artery intervention via dTRA in China.

This single-center, prospective, randomized controlled, superiority open-label study will enroll 428 consecutive patients with coronary heart disease undergoing percutaneous coronary intervention as the study population. After preoperative evaluation, the participants will be randomly divided into a study group (dTRA) and control group (TRA) in a 1:1 ratio. The primary endpoint (radial artery occlusion at 24 hours after operation) and secondary endpoint events will be evaluated and recorded.

This study has been registered in the Chinese Clinical Trial Registry (registration number: ChiCTR2300073902).

https://www.scienceopen.com/hosted-document?doi=10.15212/CVIA.2024.0015

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Minghao Liu, Huanhuan Wang and Lijian Gao et al. Protocol for a Single-Center Randomized Controlled Trial of Percutaneous Coronary Intervention Via Distal Transradial Access Versus Transradial Access. CVIA. 2024. Vol. 9(1). DOI: 10.15212/CVIA.2024.0015