Tag: premature ventricular contractions

Approaches for Localizing the Origin of PVCs in the Outflow Tract: Future Perspectives and Challenges

Announcing a new article publication for Cardiovascular Innovations and Applications journal. Idiopathic ventricular arrhythmias (IVAs) are a type of arrhythmias with focal origins. The locations of most such arrhythmias have been identified and confirmed. In cases in which pharmacological treatment is ineffective or limited, radiofrequency catheter ablation is a therapeutic option whose success rate largely depends on accurate IVA localization.

The current standard approach for localizing the origin of IVAs involves comparing the normal electrocardiogram (ECG) with the characteristic ECG of the arrhythmia. This comparison includes analysis of parameters such as the QRS wave polarity in different leads, QRS duration, R/S ratio, and S-R difference in precordial leads.

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Clinical Characteristics and Features of Idiopathic Premature Ventricular Contractions with an Enlarged Left Atrium in Patients Without Structural Heart Diseases

Announcing a new article publication for Cardiovascular Innovations and Applications journal. Idiopathic premature ventricular contractions (PVCs) may cause subtle changes in left atrium (LA) structure and function. The authors of this article investigated whether serum sodium, body mass index (BMI), N-terminal pro-B-type natriuretic peptide (NT-proBNP) and other characteristics might be associated with LA in these patients.

A total of 268 consecutive patients diagnosed with idiopathic PVCs were retrospectively analyzed. We assessed associations of enlarged LA and with the clinical features obtained from 24-hour Holter monitoring, electrocardiography and serum data in patients with PVCs.

Patients with an enlarged LA (n = 101), compared with a normal LA (n = 167), had significantly lower serum sodium (140.9 ± 3.0 mmol/L vs 141.7 ± 2.8 mmol/L; P = 0.022), higher BMI (24.5 ± 2.7 kg/m2 vs 21.7 ± 2.5 kg/m2; P < 0.001), higher NT-proBNP [99.3 (193.6) pg/mL vs 77.8 (68.8) pg/mL; P < 0.001] and lower average heart rates (73.0 ± 8.0 bpm vs 75.3 ± 7.6 bpm; P = 0.019). No significant differences were observed in P-wave dispersion, QRS duration, PVC coupling interval, pleomorphism, circadian rhythm, non-sustained ventricular tachycardia, serum potassium, serum magnesium, hypersensitive C-reactive protein, low-density lipoprotein cholesterol, symptoms and PVC duration.

Beyond the burden of PVCs, attributes such as serum sodium, BMI, NT-proBNP and average heart beats may potentially correlate with LA enlargement in individuals with idiopathic PVCs.

https://www.scienceopen.com/hosted-document?doi=10.15212/CVIA.2023.0094

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Xue Kuang, Yuxiang Long and Jinhang Che et al. Clinical Characteristics and Features of Idiopathic Premature Ventricular Contractions with an Enlarged Left Atrium in Patients Without Structural Heart Diseases. CVIA. 2024. Vol. 9(1). DOI: 10.15212/CVIA.2023.0094

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