Tag: predictive nomogram

Nomogram-Based Prediction of Mortality after Cardiac Resynchronization Therapy in Patients with Heart Failure

Nomogram-Based Prediction of Mortality after Cardiac Resynchronization Therapy in Patients with Heart FailureAnnouncing a new article publication for Cardiovascular Innovations and Applications journal.  Heart failure (HF) with reduced ejection fraction (HFrEF; LVEF ≤ 35%) affects more than 64 million people globally. The 5-year all-cause mortality exceeds 40% among this population. CRT is a cornerstone treatment for patients with HFrEF with left bundle branch block, prolonged QRS complex duration (ventricular depolarization interval ≥ 150 ms on an electrocardiogram), and New York Heart Association (NYHA) class II–IV symptoms despite optimal medical therapy. However, many patients remain at high risk of mortality post-CRT, particularly those who develop new-onset atrial fibrillation (NOAF), which can disrupt resynchronization and worsen prognosis. Existing prognostic models often do not include NOAF and may lack precision.

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