Tag: Pathophysiology

Exploring Biomarkers for Early Diagnosis of Abdominal Aortic Aneurysms

Announcing a new article publication for Cardiovascular Innovations and Applications journal examines recent advances in circulating biomarkers for the early diagnosis and risk assessment of abdominal aortic aneurysm (AAA), a largely asymptomatic but potentially life-threatening vascular condition. The authors describe how pathological processes underlying AAA—such as inflammation, vascular smooth muscle cell dysfunction, extracellular matrix degradation, and thrombosis—release measurable molecular signals into the bloodstream, creating opportunities to improve detection beyond imaging alone.

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Interventional Therapy in Pulmonary Embolism Treatment: Expanding Benefits and Advancing Safety

Interventional Therapy in Pulmonary Embolism Treatment: Expanding Benefits and Advancing SafetyAcute pulmonary embolism (PE) remains a global health challenge with significant morbidity and mortality. High-risk PE, characterized by hemodynamic instability, and intermediate-risk PE, with evidence of right ventricular (RV) dysfunction, pose distinct therapeutic challenges. Traditionally, systemic thrombolysis and surgical embolectomy have been the primary therapeutic strategies. However, both approaches come with limitations, such as bleeding risks in thrombolysis and resource-intensive requirements in surgical embolectomy. In response, percutaneous catheter-directed therapies, including mechanical thrombectomy and catheter-directed thrombolysis (CDT), have emerged as promising alternatives.

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