Tag: microRNA-1321

Genetic Analysis Reveals Key Regulatory Axis in Aortic Dissection: CBL Regulated by HOXB13 and microRNA-1321

Announcing a new article publication for Cardiovascular Innovations and Applications journal.  Aortic dissection (AD) is a fatal cardiovascular disease for which the key involved genes are largely unknown. The authors of this article aimed to identify promising AD biomarkers from high-throughput RNA expressing data.

In the GSE98770 dataset, differentially expressed mRNAs (DE-mRNAs) and microRNAs (DE-microRNAs) were identified through differentially expressed gene analysis and gene set enrichment analysis. The regulatory network between DE-mRNAs and DE-microRNAs was established, and hub genes were identified with Cytoscape.

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