Tag: ablation

Left Bundle Branch Ablation Guided by a Three-Dimensional Mapping System: A Novel Method for Establishing a Heart Failure Animal Model

Announcing a new article publication for Cardiovascular Innovations and Applications journal.  Few studies have been conducted to establish animal models of left bundle branch block by using three-dimensional mapping systems. This research reported by this article was aimed at creating a canine left bundle branch block model by using a three-dimensional mapping system.

A three-dimensional mapping system was used to map and ablate the left bundle branch in beagles. Ten canines underwent radiofrequency ablation, among which left bundle branch block was successfully established in eight, one experienced ventricular fibrillation, and one developed third-degree atrioventricular block. The maximum HV interval measured within the left ventricle was 29.00 ± 2.93 ms, and the LBP-V interval at the ablation site was 20.63 ± 2.77 ms. The LBP-V interval at the ablation target was 71.08% of the maximum HV interval.

This three-dimensional mapping system is a reliable and effective guide for ablation of the left bundle branch in dogs.

https://www.scienceopen.com/hosted-document?doi=10.15212/CVIA.2023.0066

CVIA is available on the ScienceOpen platform and at Cardiovascular Innovations and Applications. Submissions may be made using ScholarOne Manuscripts. There are no author submission or article processing fees. Cardiovascular Innovations and Applications is indexed in the EMBASE, EBSCO, ESCI, OCLC, Primo Central (Ex Libris), Sherpa Romeo, NISC (National Information Services Corporation), DOAJ, Index Copernicus, Research4Life and Ulrich’s web Databases. Follow CVIA on Twitter @CVIA_Journal; or Facebook.

Pengkang He, Han Jin and Yiran Hu et al. Left Bundle Branch Ablation Guided by a Three-Dimensional Mapping System: A Novel Method for Establishing a Heart Failure Animal Model. CVIA. 2023. Vol. 8(1). DOI: 10.15212/CVIA.2023.0066

Loading

Experience in Application of a Three-Dimensional Pulsed Field Ablation System Integrating Mapping and Ablation

Announcing a new article publication for Cardiovascular Innovations and Applications journal. Pulsed field ablation (PFA), a promising technology for ablating arrhythmias, has significantly better efficiency and potentially greater safety than traditional ablation techniques using thermal injury. However, most clinical research on PFA for ablation to date has used basket- or flower-shaped catheters, thus requiring a large introducing sheath and catheter location under fluoroscopic guidance. The authors of this article describe initial experiences with using a three-dimensional PFA system integrating mapping and ablation, and an annular catheter.

https://www.scienceopen.com/hosted-document?doi=10.15212/CVIA.2023.0009

CVIA is available on the ScienceOpen platform and at Cardiovascular Innovations and Applications. Submissions may be made using ScholarOne Manuscripts. There are no author submission or article processing fees. Cardiovascular Innovations and Applications is indexed in the EMBASE, EBSCO, ESCI, OCLC, Primo Central (Ex Libris), Sherpa Romeo, NISC (National Information Services Corporation), DOAJ, Index Copernicus, Research4Life and Ulrich’s web Databases. Follow CVIA on Twitter @CVIA_Journal; or Facebook.

Yan Wang, Jie Qiu and Daowen Wang. Experience in Application of a Three-Dimensional Pulsed Field Ablation System Integrating Mapping and Ablation. CVIA. 2023. Vol. 7(1). DOI: 10.15212/CVIA.2023.0009

Loading

Current Management of Ventricular Tachycardia: Approaches and Timing

Current Management of Ventricular Tachycardia: Approaches and Timing

Authors: John, Roy M.; Stevenson, William

Ventricular tachycardia (VT) in the presence of structural heart disease is associated with sudden cardiac death and warrants prompt attention. Implantable cardioverter defibrillators (ICDs) while highly effective in terminating sustained ventricular arrhythmias and reducing mortality, have no effect on the arrhythmia substrate and recurrent shocks for VT termination occur in approximately 20% of patients. Shocks worsen quality of life and are associated with progression of heart failure and increased mortality. Antiarrhythmic drugs, mainly in the form of beta-blockers or amiodarone, are moderately effective in reducing ICD therapies but drug intolerance and serious toxicities of amiodarone necessitate drug cessation in a quarter of patients. Catheter ablation has emerged as an effective treatment for control of frequent VT episodes and can be life saving in cases of incessant VT or VT storm. As experience increases, it is being used increasingly earlier, rather than a last resort therapy. Efficacy varies with the nature of the underlying heart disease. Intramural arrhythmia substrate and failure to create permanent ablation lesions remain challenges and repeat procedures are necessary in a third to a half of patients. For idiopathic VTs or PVCs that are symptomatic or worsen LV function, catheter ablation is often an effective therapy.

Loading

Changing the Way We “See” Scar: How Multimodality Imaging Fits in the Electrophysiology Laboratory

Changing the Way We “See” Scar: How Multimodality Imaging Fits in the Electrophysiology Laboratory

Author: Wokhlu, Anita

Substrate characterization is the mainstay of ablation for ventricular tachycardia (VT). Although the use of electroanatomic voltage mapping (EAVM) in the electrophysiology (EP) laboratory has enabled real-time approximation of myocardial scar, it has limitations. This is related to the subjective and tedious nature of voltage mapping and the challenges of defining the transmurality of scar. Various noninvasive methods of scar assessment have emerged, with magnetic resonance imaging (MRI) being the most accurate. Integrated MRI and electroanatomic voltage mapping studies demonstrate good correlation. Nonetheless, MRI has advantages. These include (1) preprocedure identification of epicardial and intramural scar, (2) assessment of ablative lesion formation after unsuccessful ablations, (3) identification of heterogeneous regions of scar, where critical conducting channels are likely to occur, and (4) predictive value in the assessment of sudden cardiac death (SCD). Integration of scar imaging in ventricular tachycardia ablation and risk stratification has great potential to advance the practice of arrhythmia management.

Loading